Medial hypothalamic nuclei mediate serotonin's inhibitory effect on feeding behavior.

@article{Leibowitz1990MedialHN,
  title={Medial hypothalamic nuclei mediate serotonin's inhibitory effect on feeding behavior.},
  author={Sarah F. Leibowitz and Gail F. Weiss and Jin Su Suh},
  journal={Pharmacology, biochemistry, and behavior},
  year={1990},
  volume={37 4},
  pages={735-42}
}
Previous studies have demonstrated that injection of serotonin (5-HT) into the paraventricular nucleus (PVN), specifically at the onset of the active feeding cycle, causes a strong and selective suppression of carbohydrate intake, while producing no change in fat intake and, in some cases, enhancing protein consumption. The purpose of the present investigation was to determine whether this selective inhibitory effect of 5-HT on macronutrient ingestion is localized to a specific brain region… CONTINUE READING