Mechanosensitive channels: multiplicity of families and gating paradigms.

  title={Mechanosensitive channels: multiplicity of families and gating paradigms.},
  author={Sergei Sukharev and David P. Corey},
  journal={Science's STKE : signal transduction knowledge environment},
  volume={2004 219},
Mechanosensitive ion channels are the primary transducers that convert mechanical force into an electrical or chemical signal in hearing, touch, and other mechanical senses. Unlike vision, olfaction, and some types of taste, which all use similar kinds of primary heterotrimeric GTP-binding protein-coupled receptors, mechanosensation relies on diverse types of transducer molecules. Unrelated types of channels can be used for the perception of various mechanical stimuli, not only in distant… CONTINUE READING

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