Mechanobiology and developmental control.

  title={Mechanobiology and developmental control.},
  author={Tadanori Mammoto and Akiko Mammoto and Donald E. Ingber},
  journal={Annual review of cell and developmental biology},
Morphogenesis is the remarkable process by which cells self-assemble into complex tissues and organs that exhibit specialized form and function during embryological development. Many of the genes and chemical cues that mediate tissue and organ formation have been identified; however, these signals alone are not sufficient to explain how tissues and organs are constructed that exhibit their unique material properties and three-dimensional forms. Here, we review work that has revealed the central… CONTINUE READING
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