Mechano-transduction of DNA hybridization and dopamine oxidation through electrodeposited chitosan network.

@article{Koev2007MechanotransductionOD,
  title={Mechano-transduction of DNA hybridization and dopamine oxidation through electrodeposited chitosan network.},
  author={Stephan T. Koev and Michael A. Powers and Hyunmin Yi and Li-qun Wu and William E. Bentley and Gary W. Rubloff and Gregory F. Payne and Reza Ghodssi},
  journal={Lab on a chip},
  year={2007},
  volume={7 1},
  pages={
          103-11
        }
}
While microcantilevers offer exciting opportunities for mechano-detection, they often suffer from limitations in either sensitivity or selectivity. To address these limitations, we electrodeposited a chitosan film onto a cantilever surface and mechano-transduced detection events through the chitosan network. Our first demonstration was the detection of nucleic acid hybridization. In this instance, we electrodeposited the chitosan film onto the cantilever, biofunctionalized the film with… CONTINUE READING

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