Mechano-sensitive linkage in excitation-contraction coupling in frog skeletal muscle.

  title={Mechano-sensitive linkage in excitation-contraction coupling in frog skeletal muscle.},
  author={Joseph D. Bruton and Jan L{\"a}nnergren and H{\aa}kan Westerblad},
  journal={The Journal of physiology},
  volume={484 ( Pt 3)},
1. Single skeletal muscle fibres of Xenopus laevis were used to investigate the involvement of a mechano-sensitive link in excitation-contraction coupling (EC coupling). 2. Fibres were stimulated by intermittent tetani until tension fell to about 40% of its initial level. Fibres were then stressed either by briefly stretching the fibres to 120% of their resting length or by exposing them to hypotonic Ringer solution ([NaCl] reduced to 80%) for 5 min. 3. In six of thirty-five stretched fibres… CONTINUE READING
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