Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism.

Abstract

The Class I and III polyhydroxybutyrate (PHB) synthases from Ralstonia eutropha and Chromatium vinosum, respectively, catalyze the polymerization of beta-hydroxybutyryl-coenzyme A (HBCoA) to generate PHB. These synthases have different molecular weights, subunit composition, and kinetic properties. Recent studies with the C. vinosum synthase suggested that… (More)

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@article{Jia2001MechanisticSO, title={Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism.}, author={Yan Jia and W. Yuan and Jolanta M Wodzinska and C. Park and A. J. Sinskey and Jane Stubbe}, journal={Biochemistry}, year={2001}, volume={40 4}, pages={1011-9} }