Mechanistic modelling of fluidized bed drying processes of wet porous granules: a review.

@article{Mortier2011MechanisticMO,
  title={Mechanistic modelling of fluidized bed drying processes of wet porous granules: a review.},
  author={S{\'e}verine Th{\'e}r{\`e}se F. C. Mortier and Thomas R De Beer and Krist V. Gernaey and Jean Paul Remon and Chris Vervaet and Ingmar Nopens},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={2011},
  volume={79 2},
  pages={
          205-25
        }
}
Fluidized bed dryers are frequently used in industrial applications and also in the pharmaceutical industry. The general incentives to develop mechanistic models for pharmaceutical processes are listed, and our vision on how this can particularly be done for fluidized bed drying processes of wet granules is given. This review provides a basis for future mechanistic model development for the drying process of wet granules in pharmaceutical processes. It is intended for a broad audience with a… CONTINUE READING
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Analysing drying unit performance in a continuous pharmaceutical manufacturing line by means of mass--energy balances.

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