Mechanistic insights into precursor messenger RNA splicing by the spliceosome

@article{Shi2017MechanisticII,
  title={Mechanistic insights into precursor messenger RNA splicing by the spliceosome},
  author={Yigong Shi},
  journal={Nature Reviews Molecular Cell Biology},
  year={2017},
  volume={18},
  pages={655-670}
}
Precursor messenger RNA (pre-mRNA) splicing is an essential step in the flow of information from DNA to protein in all eukaryotes. Research over the past four decades has molecularly delineated the splicing pathway, including characterization of the detailed splicing reaction, definition of the spliceosome and identification of its components, and biochemical analysis of the various splicing complexes and their regulation. Structural information is central to mechanistic understanding of pre… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

The effects of MicroRNA deregulation on pre-RNA processing network in multiple myeloma

Sophia Adamia, Ivane Abiatari, +7 authors Kenneth C. Anderson
  • Leukemia
  • 2019
VIEW 3 EXCERPTS
CITES BACKGROUND

Similar Papers

Loading similar papers…