Mechanistic imbalance of pulmonary vasomotor control in progressive lung injury.

@article{Fullerton1996MechanisticIO,
  title={Mechanistic imbalance of pulmonary vasomotor control in progressive lung injury.},
  author={David Fullerton and Antje Hahn and Robert C. McIntyre},
  journal={Surgery},
  year={1996},
  volume={119 1},
  pages={98-103}
}
BACKGROUND Pulmonary hypertension is the major hemodynamic feature of progressive lung injury. We hypothesized that the mechanisms of pulmonary vasorelaxation become progressively impaired in progressive lung injury. The purpose of this study was to examine the following mechanisms of pulmonary vasorelaxation in a rat model of monocrotaline-induced progressive lung injury: endothelial-dependent cyclic guanosine monophosphate-mediated relaxation (response to acetylcholine), endothelial… CONTINUE READING

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