Mechanistic approaches for mixture risk assessments-present capabilities with simple mixtures and future directions.


Mechanistic studies with simple mixtures have provided insights into the nature of interactions among chemicals that lead to non-additive effects and have elucidated the exposure conditions under which interactions are likely to occur. This paper discusses studies on four mixtures: (1) 1,1-dichloroethylene and trichloroethylene, (2) carbon tetrachloride and… (More)
DOI: 10.1016/j.etap.2003.10.004


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