Mechanistic Insights into Recognitions of Ubiquitin and Myosin VI by Autophagy Receptor TAX1BP1.

@article{Hu2018MechanisticII,
  title={Mechanistic Insights into Recognitions of Ubiquitin and Myosin VI by Autophagy Receptor TAX1BP1.},
  author={Shichen Hu and Yingli Wang and Yukang Gong and Jianping Liu and Ying Li and Lifeng Pan},
  journal={Journal of molecular biology},
  year={2018}
}
TAX1BP1, a ubiquitin-binding adaptor, plays critical roles in the innate immunity and selective autophagy. During autophagy, TAX1BP1 may not only function as an autophagy receptor to recruit ubiquitylated substrates for autophagic degradation, but also serve as a Myosin VI cargo adaptor protein for mediating the maturation of autophagosome. However, the… CONTINUE READING