Mechanistic Aspects of Folded Protein Transport by the Twin Arginine Translocase (Tat).

  • Kenneth Cline
  • Published 2015 in The Journal of biological chemistry


The twin arginine translocase (Tat) transports folded proteins of widely varying size across ionically tight membranes with only 2-3 components of machinery and the proton motive force. Tat operates by a cycle in which the receptor complex combines with the pore-forming component to assemble a new translocase for each substrate. Recent data on component and… (More)
DOI: 10.1074/jbc.R114.626820