Mechanisms underlying the specification, positional regulation, and function of the cortical hem.

@article{Subramanian2009MechanismsUT,
  title={Mechanisms underlying the specification, positional regulation, and function of the cortical hem.},
  author={Lakshmi Subramanian and Shubha Tole},
  journal={Cerebral cortex},
  year={2009},
  volume={19 Suppl 1},
  pages={i90-5}
}
The cortical hem was first described as a potential signaling center at the telencephalic midline because of an enriched expression of multiple members of the Wnt and Bmp families of morphogens, and its position at the border between the presumptive cortex and the choroid plexus. There is now definitive evidence that the cortical hem is an organizing center in the telencephalon, and that it instructs the formation of the hippocampus. In this review, we present an analysis of the molecular and… CONTINUE READING
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