Mechanisms underlying the activity-dependent regulation of locomotor network performance by the Na+ pump

@inproceedings{Zhang2015MechanismsUT,
  title={Mechanisms underlying the activity-dependent regulation of locomotor network performance by the Na+ pump},
  author={Hong-Yan Zhang and Laurence D Picton and Wen-Chang Li and Keith T Sillar},
  booktitle={Scientific reports},
  year={2015}
}
Activity-dependent modification of neural network output usually results from changes in neurotransmitter release and/or membrane conductance. In Xenopus frog tadpoles, spinal locomotor network output is adapted by an ultraslow afterhyperpolarization (usAHP) mediated by an increase in Na(+) pump current. Here we systematically explore how the interval between two swimming episodes affects the second episode, which is shorter and slower than the first episode. We find the firing reliability of… CONTINUE READING
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