Mechanisms underlying postmortem redistribution of drugs: a review.

  title={Mechanisms underlying postmortem redistribution of drugs: a review.},
  author={Anne-Laure P{\'e}lissier-Alicot and Jean-Michel Gaulier and Pierre Champsaur and Pierre Marquet},
  journal={Journal of analytical toxicology},
  volume={27 8},
Postmortem drug concentrations do not necessarily reflect concentrations at the time of death, as drug levels may vary according to the sampling site and the interval between death and specimen collection. These site- and time-dependent variations are called "postmortem redistribution" (PMR). The underlying mechanisms are complex and of different types. Passive drug release from drug reservoirs such as the gastrointestinal tract, liver, lungs, and myocardium may occur immediately after death… CONTINUE READING
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