Mechanisms underlying eosinophil trafficking and their relevance in vivo.

  title={Mechanisms underlying eosinophil trafficking and their relevance in vivo.},
  author={Denise Carmona Cara and D Negr{\~a}o-Corr{\^e}a and Mauro M Teixeira},
  journal={Histology and histopathology},
  volume={15 3},
After their formation in the bone marrow, eosinophils circulate with a short half-life and are distributed throughout the body, especially in mucosal and sub-mucosal regions. Although a small amount of these cells are normally seen in healthy tissue, blood and tissue eosinophilia is a hallmark of helminthic and allergic diseases. The role of eosinophils in the normal physiology of mucosal tissues is not understood, but there is good evidence to demonstrate that these cells protect the host at… CONTINUE READING


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