Mechanisms related to the pathophysiology and management of central hypothyroidism

Abstract

Central hypothyroidism (CH) is defined as hypothyroidism due to insufficient stimulation of the thyroid gland by TSH, for which secretion or activity can be impaired at the hypothalamic or pituitary levels. Patients with CH frequently present with multiple other pituitary hormone deficiencies. In addition to classic CH induced by hypothalamic–pituitary… (More)
DOI: 10.1038/ncpendmet0995

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