Mechanisms of virus assembly.

  title={Mechanisms of virus assembly.},
  author={Jason D. Perlmutter and Michael F. Hagan},
  journal={Annual review of physical chemistry},
Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review summarizes the physics that govern the processes by which capsids assemble within their host cells and in vitro. We describe the thermodynamics and kinetics for the assembly of protein subunits into icosahedral capsid shells and how these are modified in cases in which the capsid assembles around a nucleic acid or on… 

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