Mechanisms of vanadium action: insulin-mimetic or insulin-enhancing agent?

  title={Mechanisms of vanadium action: insulin-mimetic or insulin-enhancing agent?},
  author={Margaret C. Cam and Roger W. Brownsey and John Hugh McNeill},
  journal={Canadian journal of physiology and pharmacology},
  volume={78 10},
The demonstration that the trace element vanadium has insulin-like properties in isolated cells and tissues and in vivo has generated considerable enthusiasm for its potential therapeutic value in human diabetes. However, the mechanisms by which vanadium induces its metabolic effects in vivo remain poorly understood, and whether vanadium directly mimics or rather enhances insulin effects is considered in this review. It is clear that vanadium treatment results in the correction of several… CONTINUE READING

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