Mechanisms of the metabolic disturbances caused by hypoglycin and by pent-4-enoic acid. In vivo studies.

@article{Billington1978MechanismsOT,
  title={Mechanisms of the metabolic disturbances caused by hypoglycin and by pent-4-enoic acid. In vivo studies.},
  author={D. Billington and H. Osmundsen and H. Sherratt},
  journal={Biochemical pharmacology},
  year={1978},
  volume={27 24},
  pages={
          2891-900
        }
}
Abstract 1. In the presence of the hypoglycin metabolites methylenecyclopropylpyruvate (MCPP) and methylenecyclopropylacetate (MCPA), rat liver mitochondria oxidized palmitoyl-carnitine only as far as butyrate and at a decreased rate. Although pent-4-enoic acid (pent-4-enoate) inhibited the rate of β-oxidation of palmitoyl-carnitine by mitochondria, the oxygen uptake was consistent with the complete oxidation of the substrate. 2. The inhibition of β-oxidation by pent-4-enoate was partially… Expand
[48] 4-Pentenoic acid
Inhibition of carnitine acetyltransferase by metabolites of 4-pentenoic acid.
The antagonism of the toxicity of hypoglycin by glycine.
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References

SHOWING 1-10 OF 82 REFERENCES
Metabolic effects of hypoglycin and methylenecyclopropaneacetic acid.
Effects of 4-pentenoic acid on carbohydrate metabolism in pigeon liver homogenate.
Comparison of acylcarnitines and pyruvate as substrates for rat-liver mitochondria.
  • J. Bremer
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 1966
...
1
2
3
4
5
...