Mechanisms of the inhibitory effect of epigallocatechin-3-gallate on cultured human vascular smooth muscle cell invasion.

@article{Cheng2005MechanismsOT,
  title={Mechanisms of the inhibitory effect of epigallocatechin-3-gallate on cultured human vascular smooth muscle cell invasion.},
  author={Xian Wu Cheng and Masafumi Kuzuya and Kae Nakamura and Zexuan Liu and Qun Di and Jun Hasegawa and Mitsunaga Iwata and Toyoaki Murohara and Mitsuhiro Yokota and Akihisa Iguchi},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2005},
  volume={25 9},
  pages={1864-70}
}
OBJECTIVE Although we recently showed that the administration of catechins reduced the neointimal formation in a rat balloon-injury model, the precise molecular mechanisms are largely unknown. In the present study, we tried to determine these mechanisms using an in vitro SMC invasion system. METHODS AND RESULTS Boyden chamber assay was used to examine the effect of catechins on the invasive behavior of SMCs. The invasive activity of SMCs through collagen gel was restrained by EGCG in a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Potential benefit of (-)-epigallocatechin-3-gallate for macrovascular complications in diabetes

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas • 2017

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Similar Papers

Loading similar papers…