Mechanisms of the antinatriuretic action of physiological doses of angiotensin II in man.


1. Angiotensin II (ANG II; 1 ng min-1 kg-1) or 5% (w/v) D-glucose (placebo) was infused in six normal male volunteers, pretreated with 500 mg of lithium carbonate, who were undergoing maximal water diuresis. 2. This dose of ANG II caused a circulating increment within the physiological range (27 +/- 4 to 48 +/- 9 pmol/l). 3. Compared with placebo, ANG II… (More)


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