Mechanisms of the anorexia of aging in the Brown Norway rat.

  title={Mechanisms of the anorexia of aging in the Brown Norway rat.},
  author={Tami H Wolden-Hanson},
  journal={Physiology & behavior},
  volume={88 3},
Aging is associated with a loss of the ability to maintain homeostasis in response to physiologic and environmental disturbances. Age-related dysregulation of food intake and energy balance appears to be the result of impaired responsiveness of hypothalamic integrative circuitry to metabolic cues, which can lead to lack of appropriate food intake (the anorexia of aging) and thus to inappropriate weight loss in response to acute or chronic illness or other stressors. Using the Brown Norway (BN… CONTINUE READING

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