Mechanisms of testicular torsion and potential protective agents

  title={Mechanisms of testicular torsion and potential protective agents},
  author={E. Karaguzel and M. Kadihasanoglu and O. Kutlu},
  journal={Nature Reviews Urology},
  • E. Karaguzel, M. Kadihasanoglu, O. Kutlu
  • Published 2014
  • Medicine
  • Nature Reviews Urology
  • Testicular torsion is a urological emergency most commonly seen in adolescence, involving a decrease in blood flow in the testis resulting from torsion of the spermatic cord that can result in gonad injury or even loss if not treated in time. Testicular ischaemia–reperfusion injury represents the principle pathophysiology of testicular torsion, with ischaemia caused by twisting of the spermatic cord, and reperfusion on its subsequent release. Many cellular and molecular mechanisms are involved… CONTINUE READING
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