Mechanisms of stem cell factor and erythropoietin proliferative co-signaling in FDC2-ER cells.

@article{Joneja1997MechanismsOS,
  title={Mechanisms of stem cell factor and erythropoietin proliferative co-signaling in FDC2-ER cells.},
  author={Bhavana Joneja and Hao Chen and Dhaya Seshasayee and A L Wrentmore and Don M. Wojchowski},
  journal={Blood},
  year={1997},
  volume={90 9},
  pages={3533-45}
}
Studies of hematopoietic progenitor cell development in vivo, ex vivo, and in factor-dependent cell lines have shown that c-kit promotes proliferation through synergistic effects with at least certain type 1 cytokine receptors, including the erythropoietin (Epo) receptor. Presently, c-kit is shown to efficiently support both mitogenesis and survival in the FDCP1 cell subline, FDC2. In this system, mitogenic synergy with c-kit was observed for ectopically expressed wild-type Epo receptors (wt-ER… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 28 references

A novel , erythroid cell - specific murineitive erythropoiesis

CS Lin, SK Lim, +3 authors JJ Bieker
Genes Dev • 1996

Distinct signaling from stem cell factor and erythropoietin : c - kit and erythropoietin ACKNOWLEDGMENT receptor interactions revisited

SM Jacobs, K Penta, A Lawson, ST Sawyer
Blood • 1996

Longokit proto - oncogene product and is phosphorylated in response to stem cell factor

MF Brizzi, MG Zini, +11 authors E Brambilla
Blood • 1996

Stem cell factor Blood 87:3711

K Muta, SB Krantz, MC Bondurant, C-H Dai
Blood 86:572, • 1996
View 3 Excerpts

The sequence of the chromosomal mouse beta - globin major gene : Homologies in cap - 3 ( IL - 3 ) inhibits erythropoietin - induced differentiation in Ba / F 3 cells via the IL - 3 receptor a subunit

J Krosl, JE Damen, +4 authors P Leder
J Biol Chem • 1996

Distinct survival and maturation of erythroid precursors by preventing roles of erythropoietin, insulin-like growth factor I, and stem cell apoptosis

K Muta, SB Krantz, MC Bondurant, A Wickrema
Proc Natl Acad Sci USA 92:9623, • 1995
View 1 Excerpt

Expression cloning ofwhile stimulating proliferation

A Dubart, PH Romeo, +8 authors GG Wong
Blood • 1995

Differentiation domains of the erythropoietin receptor.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine • 1994

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