Mechanisms of spontaneous activity in developing spinal networks.

@article{ODonovan1998MechanismsOS,
  title={Mechanisms of spontaneous activity in developing spinal networks.},
  author={Michael J. O'Donovan and Nikolai Chub and Peter Wenner},
  journal={Journal of neurobiology},
  year={1998},
  volume={37 1},
  pages={
          131-45
        }
}
Developing networks of the chick spinal cord become spontaneously active early in development and remain so until hatching. Experiments using an isolated preparation of the spinal cord have begun to reveal the mechanisms responsible for this activity. Whole-cell and optical recordings have shown that spinal neurons receive a rhythmic, depolarizing synaptic drive and experience rhythmic elevations of intracellular calcium during spontaneous episodes. Activity is expressed throughout the neuraxis… CONTINUE READING
Highly Cited
This paper has 62 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 57 citations

63 Citations

0510'99'03'08'13'18
Citations per Year
Semantic Scholar estimates that this publication has 63 citations based on the available data.

See our FAQ for additional information.