Mechanisms of short-term plasticity at neuromuscular active zones of Drosophila.

@article{Hallermann2010MechanismsOS,
  title={Mechanisms of short-term plasticity at neuromuscular active zones of Drosophila.},
  author={Stefan Hallermann and Manfred Heckmann and Robert J Kittel},
  journal={HFSP journal},
  year={2010},
  volume={4 2},
  pages={72-84}
}
DURING SHORT BURSTS OF NEURONAL ACTIVITY, CHANGES IN THE EFFICACY OF NEUROTRANSMITTER RELEASE ARE GOVERNED PRIMARILY BY TWO COUNTERACTING PROCESSES: (1) Ca(2+)-dependent elevations of vesicle release probability and (2) depletion of synaptic vesicles. The dynamic interplay of both processes contributes to the expression of activity-dependent synaptic plasticity. Here, we exploited various facets of short-term plasticity at the Drosophila neuromuscular junction to dissect these two processes… CONTINUE READING
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