Mechanisms of sensory transduction in the skin

@article{Lumpkin2007MechanismsOS,
  title={Mechanisms of sensory transduction in the skin},
  author={Ellen A. Lumpkin and Michael J. Caterina},
  journal={Nature},
  year={2007},
  volume={445},
  pages={858-865}
}
Sensory neurons innervating the skin encode the familiar sensations of temperature, touch and pain. An explosion of progress has revealed unanticipated cellular and molecular complexity in these senses. It is now clear that perception of a single stimulus, such as heat, requires several transduction mechanisms. Conversely, a given protein may contribute to multiple senses, such as heat and touch. Recent studies have also led to the surprising insight that skin cells might transduce temperature… CONTINUE READING
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