Mechanisms of renal vasodilation and hyperfiltration during pregnancy: current perspectives and potential implications for preeclampsia.

@article{Conrad2005MechanismsOR,
  title={Mechanisms of renal vasodilation and hyperfiltration during pregnancy: current perspectives and potential implications for preeclampsia.},
  author={Kirk P. Conrad and Jacqueline Lindsay Novak and Lee A. Danielson and Laurie J. Kerchner and Arundhathi Jeyabalan},
  journal={Endothelium : journal of endothelial cell research},
  year={2005},
  volume={12 1-2},
  pages={57-62}
}
A thorough understanding of the renal and cardiovascular adaptations to normal gestation is essential for proper diagnosis and management of hypertensive disorders and renal diseases during pregnancy. Here, we briefly review the renal hemodynamic changes of normal pregnancy. In addition, we present new findings and current concepts related to the underlying hormonal and molecular mechanisms. Finally, we speculate on the potential contribution of these insights from normal pregnancy to the… CONTINUE READING

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