Mechanisms of renal injury and progression of renal disease in congenital obstructive nephropathy

@article{Chevalier2009MechanismsOR,
  title={Mechanisms of renal injury and progression of renal disease in congenital obstructive nephropathy},
  author={Robert L. Chevalier and Barbara A. Thornhill and Michael S. Forbes and Susan C. Kiley},
  journal={Pediatric Nephrology},
  year={2009},
  volume={25},
  pages={687-697}
}
Congenital obstructive nephropathy accounts for the greatest fraction of chronic kidney disease in children. Genetic and nongenetic factors responsible for the lesions are largely unidentified, and attention has been focused on minimizing obstructive renal injury and optimizing long-term outcomes. The cellular and molecular events responsible for obstructive injury to the developing kidney have been elucidated from animal models. These have revealed nephron loss through cellular phenotypic… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 83 CITATIONS

FILTER CITATIONS BY YEAR

2010
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations

  • Averaged 7 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 122 REFERENCES

Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade

  • R Agarwal
  • Am J Physiol 284:F863–F869
  • 2002
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…