Mechanisms of rejection: role of complement

@article{Farrar2014MechanismsOR,
  title={Mechanisms of rejection: role of complement},
  author={C. Farrar and S. Sacks},
  journal={Current Opinion in Organ Transplantation},
  year={2014},
  volume={19},
  pages={8–13}
}
  • C. Farrar, S. Sacks
  • Published 2014
  • Medicine
  • Current Opinion in Organ Transplantation
  • Purpose of reviewTo provide the reader with an up-to-date comprehensive review of recent findings that highlight advances describing how proteins of the complement cascades contribute to the pathogenesis of solid organ rejection. The review is focussed mainly on renal transplantation. Recent findingsOf note are recent advances in elucidating the interactions between anaphylatoxins and their receptors in organ transplantation; there is evidence of direct engagement of C5aR on donor tubules and… CONTINUE READING

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