Mechanisms of quinolone resistance in clinical isolates of Shigella dysenteriae.

Abstract

In gram-negative bacteria, gyrase and topoisomerase IV are primary and secondary targets, respectively, of the fluoroquinolones. In addition to the mutations in the genes encoding the target enzymes (1, 4), quinolone resistance may also be associated with increased efflux of the drugs (2, 5). Possible mechanisms of quinolone resistance were investigated in… (More)

Topics

1 Figure or Table

Cite this paper

@article{Ahamed1999MechanismsOQ, title={Mechanisms of quinolone resistance in clinical isolates of Shigella dysenteriae.}, author={Jasimuddin Ahamed and Jaya Gangopadhyay and Manikuntala Kundu and Alok Kumar Sinha}, journal={Antimicrobial agents and chemotherapy}, year={1999}, volume={43 9}, pages={2333-4} }