Mechanisms of photoreceptor death and survival in mammalian retina

@article{Stone1999MechanismsOP,
  title={Mechanisms of photoreceptor death and survival in mammalian retina},
  author={Jonathan R. Stone and Juliani Maslim and Krisztina Valter-Kocsi and Kyle Mervin and Fred H. Bowers and Yanchen Chu and Nicola Barnett and Jan Marie Provis and Geraint Lewis and Steven K. Fisher and Silvia Bisti and Claudia Gargini and Luigi Cervetto and Saul Merin and Jacob Pe{\`e}r},
  journal={Progress in Retinal and Eye Research},
  year={1999},
  volume={18},
  pages={689-735}
}
The mammalian retina, like the rest of the central nervous system, is highly stable and can maintain its structure and function for the full life of the individual, in humans for many decades. Photoreceptor dystrophies are instances of retinal instability. Many are precipitated by genetic mutations and scores of photoreceptor-lethal mutations have now been identified at the codon level. This review explores the factors which make the photoreceptor more vulnerable to small mutations of its… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 118 CITATIONS, ESTIMATED Infinity% COVERAGE

118 Citations

0510'99'03'08'13'18
Citations per Year
Semantic Scholar estimates that this publication has 118 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 164 REFERENCES

A quantitative assessment of glucose metabolism in the isolated rat retina

  • B. Winkler
  • In Les SeÂminaires Ophtalmologiques d'IPSEN,
  • 1995
Highly Influential
12 Excerpts

Comparing the ERG to retinal morphology in transgenic rats with inherited degenerations caused by mutant opsin

  • S. Nishikawa, W. Cao, +4 authors M. M. LaVail
  • Invest. Ophthal. Vis. Sci
  • 1997
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…