Mechanisms of photodynamic inactivation of a gram-negative recombinant bioluminescent bacterium by cationic porphyrins.

@article{Tavares2011MechanismsOP,
  title={Mechanisms of photodynamic inactivation of a gram-negative recombinant bioluminescent bacterium by cationic porphyrins.},
  author={Anabela Tavares and Sandra R S Dias and Carla M. B. Carvalho and M Amparo F Faustino and Jo{\~a}o P C Tom{\'e} and Maria G. P. M. S. Neves and Augusto C. Tom{\'e} and Jos{\'e} A S Cavaleiro and {\^A}ngela Cunha and Newton Carlos Marcial Gomes and Eliana Alves and Adelaide Almeida},
  journal={Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology},
  year={2011},
  volume={10 10},
  pages={1659-69}
}
Photodynamic therapy is a very promising approach to inactivate pathogenic microorganisms. The photodamage of cells involves reactive oxygen species (ROS) which are generated in situ by two main mechanisms (type I and/or type II). The mechanism responsible for the photoinactivation (PI) of a bioluminescent recombinant Escherichia coli, induced by three different cationic porphyrins, was identified in this work using a rapid method based on the monitoring of the metabolic activity of this… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…