Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of CD14 and urokinase receptor.


Pertussis toxin (PTX) has been shown previously to promote myelomonocytic cell adhesion in serum. The aim of the present study was to identify, using transforming growth factor-beta1 and 1, 25-(OH)2 vitamin D3 (TGF-beta1/D3)-primed U937 cells, the PTX-binding site(s) and the adhesion molecule(s) responsible for PTX-induced myelomonocytic cell adhesion… (More)