Mechanisms of peptide immunotherapy in allergic airways disease.

  • Mark Larché
  • Published 2014 in Annals of the American Thoracic Society


Allergen immunotherapy with whole proteins is clinically efficacious but requires a protracted treatment period because of frequent allergic adverse events. A combination of duration of treatment and adverse events leads to poor compliance. Short synthetic peptides containing the major immunodominant T cell epitopes of allergenic proteins have been shown to… (More)
DOI: 10.1513/AnnalsATS.201402-090AW


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