Mechanisms of oxidative modification of low density lipoproteins under conditions of oxidative and carbonyl stress

@article{Lankin2007MechanismsOO,
  title={Mechanisms of oxidative modification of low density lipoproteins under conditions of oxidative and carbonyl stress},
  author={Vadim Z. Lankin and Alla K. Tikhaze and V. I. Kapel’ko and G. S. Shepel’kova and Konstantin B Shumaev and Oleg M. Panasenko and Galina G. Konovalova and Yu. N. Belenkov},
  journal={Biochemistry (Moscow)},
  year={2007},
  volume={72},
  pages={1081-1090}
}
Low-molecular-weight aldehydes (glyoxal, methylglyoxal, 3-deoxyglucosone) generated on autooxidation of glucose under conditions of carbonyl stress react much more actively with amino groups of L-lysine and ε-amino groups of lysine residues of apoprotein B-100 in human blood plasma low density lipoproteins (LDL) than their structural analogs (malonic dialdehyde (MDA), 4-hydroxynonenal) resulting on free radical oxidation of lipids under conditions of oxidative stress. Glyoxal-modified LDL… 
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