Mechanisms of obesity-associated cardiovascular and renal disease.

  title={Mechanisms of obesity-associated cardiovascular and renal disease.},
  author={John E. Simon Hall and Errol D. Crook and Daniel W Jones and Marion R. Wofford and Patricia M. Dubbert},
  journal={The American journal of the medical sciences},
  volume={324 3},
Obesity is the most common nutritional disorder in the United States. Growing evidence suggests that obesity initiates a cascade of disorders including hypertension, diabetes, atherosclerosis, and chronic renal disease, many of which are interdependent. Abnormal kidney function, caused by increased renal tubular reabsorption, initiates volume expansion and increased blood pressure during excess weight gain, and the hypertension and metabolic abnormalities associated with obesity, in turn… CONTINUE READING
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