Mechanisms of neutralization of influenza virus in tracheal epithelial and BHK cells vary according to IgG concentration.

@article{Outlaw1990MechanismsON,
  title={Mechanisms of neutralization of influenza virus in tracheal epithelial and BHK cells vary according to IgG concentration.},
  author={Maureen C Outlaw and Susan J Armstrong and Nigel J. Dimmock},
  journal={Virology},
  year={1990},
  volume={178 2},
  pages={478-85}
}
The interaction of IgG-neutralized type A influenza virus with differentiated epithelial cells of mouse trachea, BHK cells, and chicken erythrocytes was studied using three mouse monoclonal antibodies (IgG2a) each directed against a different antigenic site on the hemagglutinin. At high HIU:HAU ratios virus was neutralized greater than 99%, monodisperse, and attached to tracheal epithelial and BHK cells in normal amounts. The majority (70-80%) of neutralized virus failed to attach to… CONTINUE READING

From This Paper

Topics from this paper.
2 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-2 of 2 extracted citations

Similar Papers

Loading similar papers…