Mechanisms of neuroprotection during ischemic preconditioning: lessons from anoxic tolerance.

@article{PrezPinzn2007MechanismsON,
  title={Mechanisms of neuroprotection during ischemic preconditioning: lessons from anoxic tolerance.},
  author={Miguel A. P{\'e}rez-Pinz{\'o}n},
  journal={Comparative biochemistry and physiology. Part A, Molecular & integrative physiology},
  year={2007},
  volume={147 2},
  pages={291-9}
}
Different physiological adaptations for anoxia resistance have been described in the animal kingdom. These adaptations are particularly important in organs that are highly susceptible to energy deprivation such as the heart and brain. Among vertebrates, turtles are one of the species that are highly tolerant to anoxia. In mammals however, insults such as anoxia, ischemia and hypoglycemia, all cause major histopathological events to the brain. However, in mammals even ischemic or anoxic… CONTINUE READING

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