Mechanisms of neuropathic pain.

  title={Mechanisms of neuropathic pain.},
  author={Daniel Bridges and Stephen W.N. Thompson and Andrew C. Rice},
  journal={British journal of anaesthesia},
  volume={87 1},
Neuropathic pain is de®ned as `pain initiated or caused by a primary lesion or dysfunction in the nervous system'. The spectrum of neuropathic pain covers a variety of disease states (Table 1) and presents in the clinic with a variety of symptoms. Neuropathic pain is often reported as having a lancinating or continuous burning character and is often associated with the appearance of abnormal sensory signs, such as allodynia (pain as a result of a stimulus which does not normally provoke pain… CONTINUE READING