Mechanisms of neural plasticity following brain injury

@article{Wieloch2006MechanismsON,
  title={Mechanisms of neural plasticity following brain injury},
  author={Tadeusz Wieloch and Karoly Nikolich},
  journal={Current Opinion in Neurobiology},
  year={2006},
  volume={16},
  pages={258-264}
}

2 Signalling mechanisms Glossary Brain ischemia : Decrease in blood flow to the brain that leads to brain dysfunction or cell death

TLDR
Comprehensive gene expression profiling and proteomic analyses have enabled a deeper molecular and cellular mechanistic understanding of post-injury brain regeneration, aiding the design of novel therapeutic modalities that enhance regeneration.

Injury induced plasticity in primary neuronal culture and the mature brain

TLDR
Investigation of the reactive and regenerative alterations associated with the neuronal response to structural injury and the effect of the brain penetrant microtubule-stabilizing agent Epothilone D on post-injury axonal sprouting in an in vitro model of CNS trauma demonstrated intrinsic differences in how excitatory neurons and inhibitory interneurons respond to injury.

Neuroimmune System as a Driving Force for Plasticity Following CNS Injury

TLDR
The mechanisms through which the neuroimmune system mediates plasticity after CNS injury are reviewed to offer valuable therapeutic insight into how to promote adaptive plasticity and/or diminish maladaptive plasticity, respectively.

Neural Plasticity Following Ischemia

TLDR
The various ways that the existing network can be restructured and neuronal connections can be remodeled after the injury to enable partial or complete recovery of motor function are discussed.

Experience-dependent neural plasticity in the adult damaged brain.

Neural plasticity after peripheral nerve injury and regeneration

Influence of Inflammation on Poststroke Plasticity

TLDR
This paper attempts to discuss the influence of poststroke inflammatory response on brain plasticity and stroke outcome, and describes the recent anti-inflammatory strategies that have been effective for recovery in experimental stroke.

Neuron-Astrocyte Signaling in the Development and Plasticity of Neural Circuits

TLDR
Insight into the molecular mechanisms by which astrocytes regulate the wiring of the brain during development could lead to new therapeutic strategies to promote repair and rewiring of neural circuits in the mature brain following CNS injury and neurodegenerative disease.
...

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