Mechanisms of murine lacrimal gland repair after experimentally induced inflammation.

  title={Mechanisms of murine lacrimal gland repair after experimentally induced inflammation.},
  author={Driss Zoukhri and Amanda Fix and Joseph Alroy and Claire Larkin Kublin},
  journal={Investigative ophthalmology & visual science},
  volume={49 10},
PURPOSE The authors recently reported that a severe inflammatory response resulting in substantial loss of acinar cells was induced by a single injection of interleukin-1alpha into the lacrimal gland and that this effect was reversible. The purpose of the present study was to determine the mechanisms involved in lacrimal gland injury and repair. METHODS Inflammation was induced by direct injection of recombinant human interleukin-1alpha (IL-1alpha, 1 microg in 2 microL) into the exorbital… CONTINUE READING
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