Mechanisms of motor dysfunction after transient MCA occlusion: persistent transmission failure in cortical synapses is a major determinant.

@article{Bolay1998MechanismsOM,
  title={Mechanisms of motor dysfunction after transient MCA occlusion: persistent transmission failure in cortical synapses is a major determinant.},
  author={Hayrunnisa Bolay and Turgay Dalkara},
  journal={Stroke},
  year={1998},
  volume={29 9},
  pages={1988-93; discussion 1994}
}
BACKGROUND AND PURPOSE Failure of prompt motor recovery after spontaneous recirculation or thrombolytic therapy may be due to an unsatisfactory restoration of synaptic activity within cortex and/or blockade of electrical impulses at the severely ischemic subcortical region. METHODS Afferent, efferent, and synaptic activities were focally examined within the rat sensorimotor cortex by recording the somatosensory-evoked potential (SEP) and motor area response evoked by stimulation of premotor… CONTINUE READING
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Anterior circulation u large artery occlusive disease and embolism

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