Mechanisms of monooxygenase induction and inhibition.

  title={Mechanisms of monooxygenase induction and inhibition.},
  author={Klaus Netter},
  journal={Pharmacology & therapeutics},
  volume={33 1},
The mechanisms of monooxygenase induction and inhibition have been discussed from the standpoint of historic development, from the current concepts about the molecular mechanism of enzyme induction, and from the various possibilities by which inhibitors can interact with the complex cytochrome P-450 monooxygenase system. In detail the main features and phenomena of induction and of the induced new enzyme protein are briefly described, whereby general principles are emphasized. The current… CONTINUE READING

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