Mechanisms of microRNA turnover.

  title={Mechanisms of microRNA turnover.},
  author={Maryam Sanei and Xuemei Chen},
  journal={Current opinion in plant biology},
MicroRNAs (miRNAs) are 20-24 nucleotide (nt) RNAs that regulate gene expression by guiding Argonaute (AGO) proteins to specific target RNAs to cause their degradation or translational repression. The abundance of miRNAs is strictly controlled at the transcriptional or post-transcriptional levels. miRNA turnover is presumably a necessary means to regulate… CONTINUE READING