Mechanisms of lithogenic bile formation in American Indian women with cholesterol gallstones.

@article{Grundy1972MechanismsOL,
  title={Mechanisms of lithogenic bile formation in American Indian women with cholesterol gallstones.},
  author={Scott M Grundy and Allan L. Metzger and R D Adler},
  journal={The Journal of clinical investigation},
  year={1972},
  volume={51 12},
  pages={3026-43}
}
Hepatic secretions of biliary lipids were estimated in 43 patients with and without cholesterol gallstones. Studies were carried out by a marker dilution technique employing duodenal intubation with a three-lumen tube. Hourly secretion rates of cholesterol, bile acids, and phospholipids were determined during constant infusion with liquid formula. In 17 American Indian women with gallstones, hourly outputs of biliary bile acids were significantly less than those in 7 Indian men and 12 Caucasian… CONTINUE READING

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The physicochemical basis of cholesterol gallstone formation in man.

The Journal of clinical investigation • 1968
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