Mechanisms of leukocyte sequestration in inflamed lungs.

@article{Doerschuk2001MechanismsOL,
  title={Mechanisms of leukocyte sequestration in inflamed lungs.},
  author={Claire M Doerschuk},
  journal={Microcirculation},
  year={2001},
  volume={8 2},
  pages={
          71-88
        }
}
The lungs are an important site of host defense. The capillary blood contains an increased concentration of neutrophils and other leukocytes compared with large vessels, due to the structure of the pulmonary capillary bed, the diameter of spherical leukocytes, and their poor deformability compared with erythrocytes. During inflammation within the distal airways, neutrophils sequester within the pulmonary capillaries and emigrate into the parenchyma. This sequential process involves complex… CONTINUE READING
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