Mechanisms of innate resistance to Toxoplasma gondii infection.

  title={Mechanisms of innate resistance to Toxoplasma gondii infection.},
  author={J. -P. Alexander and Tanya M. Scharton-Kersten and George S. Yap and Craig W Roberts and Foo Yew Eddy Liew and Alan Sher},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  volume={352 1359},
The interaction of protozoan parasites with innate host defences is critical in determining the character of the subsequent infection. The initial steps in the encounter of Toxoplasma gondii with the vertebrate immune system provide a striking example of this important aspect of the host-parasite relationship. In immuno-competent individuals this intracellular protozoan produces an asymptomatic chronic infection as part of its strategy for transmission. Nevertheless, T. gondii is inherently a… CONTINUE READING


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