Mechanisms of injury in hypoxic-ischemic encephalopathy: implications to therapy.

  title={Mechanisms of injury in hypoxic-ischemic encephalopathy: implications to therapy.},
  author={David M. Greer},
  journal={Seminars in neurology},
  volume={26 4},
  • D. Greer
  • Published 1 September 2006
  • Medicine, Biology
  • Seminars in neurology
Cardiac arrest survivors commonly suffer ischemic brain injury, and understanding the mechanisms of injury is essential to providing insight for effective therapies for brain protection. Injury can occur at the time of the cardiac arrest and is dependent not only on the duration but also the degree of impaired circulation. Injury can be ongoing even after the return of spontaneous circulation, giving the clinician an additional window of opportunity to treat and protect the injured brain. This… 

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